| DATE |
Lecturer |
Topic |
Handouts |
Readings |
Notes |
|
|
|
|
|
|
| Jan 30 |
Kolter |
Intro to Microbial World |
handouts |
readings |
|
| Feb 1 |
Kolter |
Microbial Diversity |
handouts |
readings |
|
| Feb 4 |
Kolter |
Bacterial Cell Structure |
handouts |
readings |
|
| Feb 6 |
Kolter |
Bacterial Behaviors |
handouts |
readings |
|
| Feb 8 |
Kolter |
Cell-Cell Communication |
handouts |
readings |
|
| Feb 11 |
Kolter |
Bacterial Development |
handouts |
readings |
|
| Feb 13 |
Kolter |
Bacterial Multicellularity |
handouts |
problem set |
|
| Feb 15 |
Kolter |
PAPER DISCUSSION |
PaperDiscussion2008.pdf |
| Feb 18 |
Holiday - President’s Day |
| Feb 20 |
Rudner |
What makes an organism a model organism? sporulation in B. subtilis |
|
|
|
| Feb 22 |
Rudner |
Paper Discussion: Cell Division in Bacteria |
|
readings |
- Bernhardt and de Boer paper is "paper for discussion"
- the other two are extra reading
|
| Feb 25 |
Rudner |
Checkpoint pathways |
|
readings |
- Hartwell&Weinert and the Hughes papers are required reading
|
| Feb 27 |
Rudner |
Signal Transduction: two-component signaling pathways and others |
|
readings |
- Hoch 1991 paper is "required reading"
|
| Feb 29 |
Rudner |
Chromosome (and plasmid) organization and segregation |
|
readings |
- "Garner 2007" and the "Gerdes 2002" are required reading
|
| Mar 3 |
Rudner |
Protein Localization in Bacteria |
|
readings |
- Elowitz, Rasking, bacterial shape papers are required reading
|
| Mar 5 |
Bernhardt |
Biogenesis of the cell envelope |
|
|
|
| Mar 7 |
Lory |
Functional genomics |
powerpoint |
|
|
| Mar 10 |
Lory |
Horizontal gene transfer |
powerpoint |
readings |
|
| Mar 12 |
Lory |
Paper discussion |
powerpoint |
readings |
|
| Mar 14 |
Lory |
Genome evolution |
powerpoint |
readings |
|
| Mar 17 |
Lory |
Translational regulation |
powerpoint |
readings |
|
| Mar 19 |
Lory |
Second messengers and signaling |
|
readings |
|
| Mar 21 |
Lory |
Second messengers and signaling (cont.) |
|
readings |
|
| Mar 24 |
No Class Spring recess |
| Mar 26 |
| Mar 28 |
| Mar 30 |
Lory |
Paper discussion |
|
readings |
|
| Apr 2 |
Hochschild |
Transcription initiation (lecture) |
|
readings |
|
| Apr 4 |
Hochschild |
Paper discussion: Transcription activation and repression |
|
readings |
|
| Apr 7 |
Hochschild |
Multiple roles for the σ subunit of RNAP (research lecture) |
|
readings |
take home exam |
| Apr 9 |
Hochschild |
Paper discussion: Anti-σ factors |
|
readings |
|
| Apr 11 |
Beckwith |
Fundamentals of bacterial genetics I |
|
readings |
|
| Apr 14 |
Beckwith |
Fundamentals of bacterial genetics II |
powerpoint |
|
|
| Apr 16 |
Beckwith |
Gene fusions for all purposes |
|
readings |
|
| Apr 18 |
Beckwith |
The general secretory pathway |
powerpoint |
|
|
| Apr 21 |
Beckwith |
Papers: Disulfide bond formation and story-telling |
problem set |
readings |
|
| Apr 23 |
Goldberg |
Specialized secretion systems of bacteria |
|
readings |
|
| Apr 25 |
Goldberg |
No class |
|
|
|
| Apr 28 |
Goldberg |
Hijacking the cellular actin assembly machinery |
|
readings |
|
| Apr 30 |
Goldberg |
Paper discussion |
|
readings |
|
| May 2 |
Wessels |
Biology of streptococcal capsules. |
|
readings |
|
| May 5 |
Comstock |
Bacterial glycan synthesis, genetics and regulation. |
|
readings |
|
| May 7 |
Kasper |
Bacterial polysaccharides and the immune system |
|
readings |
|
| May 9 |
Collier |
Toxins I |
|
readings |
|
| May 11 |
Collier |
Toxins II |
|
|
|
| May 14 |
Collier |
Adhesins |
|
|
|
| May 16 |
Lencer |
Toxin transport |
|
|
|