Harvard Medical School
Kolter Lab


Abigail Trejo Hernández: Microbial Community Metabolites

Microbes produce specialized metabolites, which have been used as therapy against infections. Genomics has revealed that many microorganisms contain specialized metabolite biosynthetic gene clusters. Therefore, these microorganisms constitute a potential source of new compounds that could impact human health. However in laboratory conditions these metabolites are not produced. We are interested in developing strategies to stimulate the expression of gene clusters for the synthesis of natural products that have not been characterized.